EMCrit RACC
EMCrit 345 - March 10, 2023 By Scott Weingart
Multicenter, randomized, unblinded superiority trial.
Inclusion
- Patients over 18 years old with either a suspected or confirmed infection and sepsis-induced hypotension (SBP<100 after 1 liter fluid)
Pertinent Exclusion
- More than 3L of IVF prior to enrollment (including EMS fluids)
- Fluid Overload
- Severe volume depletion from non-sepsis causes
Intervention and Comparison
Both groups received 1-3 L of fluid prior to randomization
3 Big Sepsis Trials (PROMISE, ARISE, PROCESS) got between 2-3 liters of fluid
Ran the Protocol for 24 hours